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About the Research Resource


The collaborative Resource projects on the following list were selected based on their capacity to benefit from the Resource's capabilities, their scientific and biomedical relevance, and their ability to challenge the core technology and specific technological aims within the Resource:

Proteomics to Characterize and Understand the Host-Pathogen Interactome at the Intestinal Epithelial Surface Following Surgical Injury
John C. Alverdy, M.D.
Department of Surgery
University of Chicago Medicine, Chicago, Illinois

Analysis of Cerebral Spinal Fluid Proteome in a Preclinical Nonhuman Primate Model of Stroke
Frances Rene Bahat, Ph.D. AND
Mary P. Stenzel-Poore, Ph.D.
Department of Molecular Microbiology and Immunology
Oregon Health and Science University , Portland, Oregon

Risk Factors, Pathology, and Clinical Expression of Alzheimer’s Disease
David Bennett, M.D.
Rush Alzheimer’s Disease Center
Rush University Medical Center, Chicago, Illinois AND
Philip De Jager, M.D.
De Jager Laboratory
Brigham and Women’s Hospital
Harvard Medical School, Boston, Massachusetts

Turnover Rates in the Protein Pool of C. Elegans with Extreme Lifespan
Bart P. Braeckman, Ph.D.
Department of Biology
Ghent University, Ghent, Belgium

Proteomic Study of Hepatic Metabolism Regulated by Hypothalamic Pathways
Christoph Buettner, M.D.
Buettner Laboratory for Metabolism and Diabetes
The Mount Sinai Hospital, New York, New York

Comparative Proteomics to Define Adaptations to Purine Stress in Leishmania
Nicola S. Carter, Ph.D.
Department of Biochemistry and Molecular Biology
Oregon Health and Science University , Portland, Oregon

Degradomic and Peptidomic Biomarkers for Early-Stage Breast Cancer
Francisco J. Esteva, M.D., Ph.D.
Department of Medicine
NYU Langone Medical Center, New York, New York

Pilot Functional Proteomics Study of the Molecular Mechanisms of SHANK3 in Autism
Guoping Feng, Ph.D.
Department of Brain and Cognitive Sciences
McGovern Institute for Brain Research at MIT, Cambridge, Massachusetts AND
Jen Pan, Ph.D.
Stanley Center for Psychiatric Research
Broad Institute, Cambridge, Massachusetts

Pathogenesis of Bacterial Vaginosis and Integrated Omics
David N. Fredricks, M.D.
Vaccine and Infectious Disease Division
Fred Hutchinson Cancer Research Center, Seattle, WA

Phosphoproteome Analysis of Self-Fusion Regulation in Neurospora crassa
N. Louise Glass, Ph.D.
Department of Plant and Microbial Biology
University of California, Berkeley

Functional Annotation of Mtb Drug Resistant Strains
Christophe Grundner, Ph.D.
Seattle BioMed, Seattle, Washington

Mitochondrial Proteomic Profile Changed by JNK Interaction with Sab
Neil Kaplowitz, Ph.D.
University of Southern California, Los Angeles, California

Deciphering the Regulation Code of the New Oncogene EIF5A Using Intact Protein-Level Measurements and Advanced Proteomics Platforms
Richard Klemke, Ph.D.
Department of Pathology and Moores Cancer Center
University of California, San Diego, California

Characterization of the SATB1 Phosphorylations upon Ionization Radiation
Terumi Kohwi-Shigematsu, Ph.D.
Lawrence Berkeley National Laboratory, Berkeley, California

Single Islet Proteomics for Investigating the Mechanisms of Beta-Cell Function AND
Examination of LIRKO Islets and Serum Using Quantitative Proteomics Approaches
Rohit N. Kulkarni, M.D., Ph.D.
Joslin Diabetes Center, Boston, Massachusetts

Proteomic Analysis of Pseudomonas aeruginosa Persisters
Kim Lewis, Ph.D.
Department of Biology
Northeastern University , Boston, Massachusetts

Pilot Study for Identifying Urinary Prostate Cancer Biomarkers
Alvin Y. Liu, Ph.D.
Department of Urology
University of Washington, Seattle, Washington

Analsysis of eIF3 Complex Formation and Subunit Modifications during T Lymphocyte Activation
Suzanne Miyamoto, Ph.D.
Department of Internal Medicine
University of California Davis Health System, Sacramento, California

Discovery of Oncogenic Viruses
Patrick S. Moore, M.D., Ph.D.
Cancer Virology Program
University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania

Quantitative Proteomics of Alzheimer’s Disease Human Brain
Amanda Myers, Ph.D.
Department of Psychiatry and Behavioral Sciences
Miller School of Medicine , University of Miami, Coral Gables, Florida

Defining the Cytoprotective Mechanisms of Action of Natural and Synthetic Compounds
Stephen J. Polyak
Department of Laboratory Medicine
University of Washington, Seattle, Washington

HIV Proteomic Center for Host-Viral Response Characterization
Richard W. Price
Department of Neurology
University of California, San Francisco, California

Identifying Biomarkers of Heterogeneous Drug Response in Non-Small-Cell Lung Cancer
Vito Quaranta, M.D. AND Katherine Jameson, Ph.D.
The Quaranta Lab
Department of Cancer Biology
Vanderbilt University Medical Center, Nashville, Tennessee

System Analysis of Protein Phosphorylation Involved in Sperm Maturation
Kenneth Roberts, Ph.D.
Medical Sciences
Washington State University , Pullman, Washington

Regulatory Protein Quantification in Trail-Mediated Apoptosis
Peter Sorger, Ph.D. AND Mario Niepel, Ph.D.
Sorger Lab
Department of Systems Biology
Harvard Medical School , Boston, Massachusetts

Breast Cancer Response to Signal Transduction Therapy
Paul T. Spellman, Ph.D.
Department of Computational Biology
Oregon Health and Science University, Portland, Oregon

Phosphoproteome Analysis to Identify Signaling Cascades Associated with Ultrasound Therapy
Kent Thornberg, Ph.D.
The Moore Institute
Oregon Health and Science University , Portland, Oregon

Proteomic Profiling to Understand Iron Metabolism in Breast Cancer
Suzy V. Torti, Ph.D.
Department of Molecular and Cell Biology AND
Reinhard C. Laubenbacher, Ph.D.
Center for Quantitative Medicine
University of Connecticut Health Center, Farmington, Connecticut

Proteomic Analysis of Alcoholic Hepatitis in the Mouse Model
Hidekazu Tsukamoto, D.V.M, Ph.D.
Department of Pathology
Keck School of Medicine of University of Southern California, Los Angeles, California